Parathyroid hormone is involved in (A) Demineralization (B) Bone resorption (C) Both A and B (D) Antibodies production

Question:

Parathyroid hormone is involved in 

(A) Demineralization 

(B) Bone resorption 

(C) Both A and B 

(D) Antibodies production 

Answer:

Correct option: (C) Both A and B

Explanation:

Calcium and phosphorus homeostasis are maintained by the influence of parathyroid hormone on bone tissue and on the kidneys. An overabundance of the hormone causes demineralization of the bone tissue and the depletion of calcium and phosphorus from the body. Excess phosphorus is excreted by the kidneys. 

Parathyroid hormone regulates serum calcium through its effects on bone, kidney, and the intestine: In bone, PTH enhances the release of calcium from the large reservoir contained in the bones. Bone resorption is the normal destruction of bone by osteoclasts, which are indirectly stimulated by PTH.

PTH stimulates bone remodeling overall, bone resorption predominates when continuous exposure to high levels of PTH ensues, whereas administration of low, intermittent doses of PTH leads to a net increase in bone mass.

Hence, Option (C) Both A and B is the correct answer.